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Diluting Methadone To Liquid Form – Practice, Negative Impact, Diversion
ByAdminAdmin 12/28/2021The dilution of methadone with water was initiated as a result of the first federal methadone regulations because it was believed that this policy would reduce the diversion of methadone. While initially this policy may have had an impact within a short time most prospective buyers learning that methadone was now diluted with water and…
The Body’s Own Opiates: Understanding Endorphins and the Runner’s High
ByAdminAdmin 03/10/2026Human beings have always searched for ways to feel better, reduce pain, and experience moments of happiness or even euphoria. Throughout history people have discovered substances that influence the brain and body, including powerful drugs known as opioids. However, what many people do not realize is that the human body itself produces chemicals that act…
Dear Doctor Letter by J. Thomas Payte, M.D.
ByAdminAdmin 01/05/2023Education Series Number 9 January 1999 Letter Supplement O N Y O U R L E T T E R H E A D Dear Doctor: The bearer of this letter is a patient in a methadone maintenance treatment program. Methadone patients frequently need treatment for other medical, surgical, and dental conditions. At times the health professional…
Methadone 101
ByAdminAdmin 07/06/2022Course Readings Lesson 1: Brief History of Methadone Maintenance Treatment A short introduction about how methadone started. The original team consisted of four and included Drs. Dole and Nyswander who were the investigators, Dr. Herman Joseph who did the statistics and Dr. Mary Jeanne Kreek who was a medical student at the time. Lesson 2: Methadone…
MARS Medicated Assisted Recovery Services Project
ByAdminAdmin 10/22/2022The peer facilitated Medication Assisted Recovery Services Project (MARS) is a collaboration between the National Alliance of Methadone Advocates (NAMA) and the Albert Einstein College of Medicine (AECOM), Division of Substance Abuse (DoSA). MARS is located in the Bronx, NY and will provide peer recovery support services to patients at AECOM’s Methadone Maintenance Treatment Programs….
The Pharmacology of Opioids
ByAdminAdmin 04/18/2023Basic Pharmacology: How Methadone Works Part 2 Basic Opioid Pharmacology All natural and synthetic opioids exhibit a three dimensional T-shaped configuration (Barchas, Berger, Ciaranello and Elliott, 1977). This T-shaped molecule has two broad hydrophobic surfaces which are at right angles and a methylated nitrogen which is usually charged at physiological pH. The charged nitrogen is…