Methadone Clinics in Louisville

Name rehabsAddressPhone
Center for Behavioral Health KY Inc1402 Browns Lane Suite A Louisville, KY 40207(502) 894-0234
David Harmon and AssociatesProfessional Centre Building 3934 Dixie Highway Suite 310 Louisville, KY 40216(502) 896-8006
Interlink Counseling Services Inc8311 A and B Preston Highway Louisville, KY 40219(502) 964-7147
Methadone/Opiate Rehabilitation and Education Center (MORE)1448 South 15th Street, Louisville, KY 40210(502) 574-6414

Rules and Regulations

Louisville adheres to strict federal and state regulations regarding methadone clinics, outlined by the Drug Enforcement Administration (DEA) and the Kentucky Board of Pharmacy.

Certification Procedures

  • Methadone clinics must register with the DEA and acquire a certification of approval to dispense methadone
  • Clinics must adhere to record-keeping and security requirements around storing and dispensing methadone
  • Staff must undergo training on methadone treatment protocols and counseling methods

Benefits of Medication-Assisted Treatment

Methadone and other medication-assisted treatments for opioid addiction can:

  • Reduce opioid cravings and withdrawal symptoms
  • Allow people to focus on their health and participation in counseling
  • Greatly reduces the risk of overdose and death
  • Help people regain stability and improve functionality in their daily lives

How Clinics Operate and Their Purpose

Methadone clinics provide daily doses of methadone to treat opioid addiction. Clinics also provide counseling and support services to help patients recover. The ultimate purpose is to help patients achieve sobriety and no longer need methadone treatment.

Insurance Coverage

Most private insurance plans and Medicaid cover methadone treatment. Some clinics also offer treatment on a sliding scale based on income for those without insurance.

Drug Use in Louisville

The Opioid Crisis

The opioid crisis declared a public health emergency

  • In 2017, Kentucky had one of the nation’s highest drug overdose death rates at 37.2 per 100,000 people
  • Over 1,500 overdose deaths in Kentucky in 2021, with the majority involving fentanyl

Statistics on Drug Overdoses and Deaths

In Jefferson County specifically:

  • 812 overdose deaths in 2021
  • The majority involved fentanyl, methamphetamine, or a combination

Jefferson County’s overdose death rate remains above the state average.

Addiction Treatment Overview

Inpatient Treatment

  • Medically-managed detox and behavioral therapies
  • Typical stay 14-28 days
  • 24/7 medical monitoring and counseling

Outpatient Treatment

  • Periodic counseling and group therapy sessions
  • Varies from weekly to monthly visits
  • Offered through clinics, rehab centers, and private practices

Treatment Level Unreported

  • Estimated 40% of Kentuckians needing treatment don’t receive it
  • Stigma, cost, and access issues are barriers

Comparison of Treatment in Louisville vs. Indianapolis and Cincinnati

Treatment centers145256223
Inpatient beds8501,1501,723
Cost of treatment$7,500/month$6,000/month$9,000/month

Methadone Treatment

What is Methadone

Methadone is a long-acting opioid agonist medication used to treat opioid use disorder and prevent withdrawal symptoms. It binds to opioid receptors in the brain, reducing cravings and blocking the euphoric effects of other opioids. Methadone is taken orally once daily in opioid treatment programs (OTPs).

Methadone maintenance treatment provides a legally obtained, orally effective opioid substitute to stabilize patients and avoid the peaks and valleys of short-acting opioids. This allows patients to function normally, attend counseling, and avoid using illegal opioids. Methadone is only provided through regulated OTPs requiring counseling and urine drug screening.

Methadone has controversy regarding its use in treating addiction. Some view it as merely substituting one opioid for another. However, research shows methadone relieves cravings and withdrawal, allowing patients to regain health, employment, and relationships. Careful patient selection and program regulations prevent misuse.

Methadone Distribution

Description of monitoring and regulations:

  • Urine testing: Methadone maintenance patients must undergo at least eight tests in the first year of treatment to ensure no illegal opioid use.
  • Take-home requirements: During the first 14 days of treatment, the take-home supply of methadone is limited to a 24-hour supply. After 90 days of compliance, patients can earn one take-home dose per week, eventually earning up to 30 take-home doses for stable patients.
  • Monitoring: Methadone treatment programs should have an interprofessional team including physicians, nurses, and counselors to coordinate care.
  • Prescription drug monitoring: Clinicians should review prescription drug monitoring program (PDMP) data to carefully cross-reference opioid dosage, as methadone has a narrow therapeutic window and overdose risk.

Methadone Treatment Effectiveness Research

Methadone is an effective medication for treating opioid use disorder used since 1947. Studies show methadone reduces opioid use, disease transmission, and crime when properly regulated.

Evidence for Effectiveness

Studies show participation in a methadone program results in 33% fewer opioid-positive drug tests. Patients on methadone are 4.44 times more likely to stay in treatment. Retention in treatment reduces overdose risk, HIV and Hepatitis C transmission through IV drug use and unemployment.

Major Drawbacks

Potential for misuse/diversion if not properly regulated. Severe withdrawal symptoms if stopped suddenly, require a gradual taper. Possible QTc prolongation or cardiac arrhythmias. Respiratory depression and overdose risk when combined with alcohol or benzodiazepines.

Comparison to Other Medications

Methadone and buprenorphine are equally effective in reducing illicit opioid use. Buprenorphine has a lower risk of overdose and can be prescribed in office-based settings.

Methadone has demonstrated effectiveness but also risks requiring careful patient selection and management through a highly structured program.

About Louisville

Location, County & List of Neighboring States

Louisville is located in north central Kentucky on the Ohio River along the Indiana border. It is the county seat of Jefferson County. Louisville borders the following states:

  • Indiana
  • Illinois
  • Ohio
  • West Virginia
  • Tennessee

Capital and Largest City

Louisville is the largest city in Kentucky and serves as the state’s main economic and cultural center.

Land Area

The land area of Louisville is approximately 398 square miles.


Key infrastructure in Louisville includes:

  • Louisville International Airport
  • Port of Louisville – one of the largest inland ports in the U.S.
  • Interstate highways I-64, I-65 and I-71
  • Public transportation system (buses and trolleys)

Population Statistics

Total Population

The population of Louisville is approximately 615,366 (2020).



  • Male: 48.8%
  • Female: 51.2%

Age Brackets

  • Under 18 years: 21.2%
  • 18 to 65 years: 63.3%
  • Over 65 years: 15.5%


Major occupations in Louisville include healthcare, transportation and logistics, manufacturing, food services, and retail.