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Methadone Take Home Bottle Recall
ByAdminAdmin 02/17/2023The intent of Bottle Recall initially was to be able to allow patients take home medication and to insure that methadone is not diverted to the streets. However, methadone programs have been giving patients take home medication for years without a serious methadone diversion problem. Furthermore numerous studies have demonstrated that methadone is not a…
Patient Success Stories in Outpatient Medication-Assisted Treatment (MAT)
ByAdminAdmin 03/10/2026Substance use disorders, particularly opioid dependence, remain a major public health challenge worldwide. One of the most effective and evidence-based approaches to treating opioid addiction is Medication-Assisted Treatment (MAT). MAT combines FDA-approved medications with counseling and behavioral therapies to treat substance use disorders comprehensively. Outpatient MAT programs allow patients to receive treatment while continuing their…
The Pharmacology of Opioids
ByAdminAdmin 04/18/2023Basic Pharmacology: How Methadone Works Part 2 Basic Opioid Pharmacology All natural and synthetic opioids exhibit a three dimensional T-shaped configuration (Barchas, Berger, Ciaranello and Elliott, 1977). This T-shaped molecule has two broad hydrophobic surfaces which are at right angles and a methylated nitrogen which is usually charged at physiological pH. The charged nitrogen is…
Methadone 101
ByAdminAdmin 07/06/2022Course Readings Lesson 1: Brief History of Methadone Maintenance Treatment A short introduction about how methadone started. The original team consisted of four and included Drs. Dole and Nyswander who were the investigators, Dr. Herman Joseph who did the statistics and Dr. Mary Jeanne Kreek who was a medical student at the time. Lesson 2: Methadone…
Dear Doctor Letter by J. Thomas Payte, M.D.
ByAdminAdmin 01/05/2023Education Series Number 9 January 1999 Letter Supplement O N Y O U R L E T T E R H E A D Dear Doctor: The bearer of this letter is a patient in a methadone maintenance treatment program. Methadone patients frequently need treatment for other medical, surgical, and dental conditions. At times the health professional…
Diluting Methadone To Liquid Form – Practice, Negative Impact, Diversion
ByAdminAdmin 12/28/2021The dilution of methadone with water was initiated as a result of the first federal methadone regulations because it was believed that this policy would reduce the diversion of methadone. While initially this policy may have had an impact within a short time most prospective buyers learning that methadone was now diluted with water and…