The intent of Bottle Recall initially was to be able to allow patients take home medication and to insure that methadone is not diverted to the streets. However, methadone programs have been giving patients take home medication for years without a serious methadone diversion problem. Furthermore numerous studies have demonstrated that methadone is not a…

Basic Pharmacology:  How Methadone Works Part 2 Basic Opioid Pharmacology All natural and synthetic opioids exhibit a three dimensional T-shaped configuration (Barchas, Berger, Ciaranello and Elliott, 1977). This T-shaped molecule has two broad hydrophobic surfaces which are at right angles and a methylated nitrogen which is usually charged at physiological pH. The charged nitrogen is…

Human beings have always searched for ways to feel better, reduce pain, and experience moments of happiness or even euphoria. Throughout history people have discovered substances that influence the brain and body, including powerful drugs known as opioids. However, what many people do not realize is that the human body itself produces chemicals that act…

Education Series Number 9 January 1999 Letter Supplement O N  Y O U R  L E T T E R H E A D Dear Doctor: The bearer of this letter is a patient in a methadone maintenance treatment program. Methadone patients frequently need treatment for other medical, surgical, and dental conditions. At times the health professional…