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Blind Dosing
ByAdminAdmin 05/05/2023Methadone maintenance treatment has been the most effective treatment for addiction to heroin resulting the cessation of heroin use and criminal behavior. Prior to the development of methadone maintenance treatment over 28 years ago narcotic addiction was considered incurable and a behavioral disorder under the control of law enforcement. Drs. Dole and Nyswander brought the…
Dear Doctor Letter by J. Thomas Payte, M.D.
ByAdminAdmin 01/05/2023Education Series Number 9 January 1999 Letter Supplement O N Y O U R L E T T E R H E A D Dear Doctor: The bearer of this letter is a patient in a methadone maintenance treatment program. Methadone patients frequently need treatment for other medical, surgical, and dental conditions. At times the health professional…
The Pharmacology of Opioids
ByAdminAdmin 04/18/2023Basic Pharmacology: How Methadone Works Part 2 Basic Opioid Pharmacology All natural and synthetic opioids exhibit a three dimensional T-shaped configuration (Barchas, Berger, Ciaranello and Elliott, 1977). This T-shaped molecule has two broad hydrophobic surfaces which are at right angles and a methylated nitrogen which is usually charged at physiological pH. The charged nitrogen is…
Methadone 101
ByAdminAdmin 07/06/2022Course Readings Lesson 1: Brief History of Methadone Maintenance Treatment A short introduction about how methadone started. The original team consisted of four and included Drs. Dole and Nyswander who were the investigators, Dr. Herman Joseph who did the statistics and Dr. Mary Jeanne Kreek who was a medical student at the time. Lesson 2: Methadone…
Grievance Report
ByAdminAdmin 04/02/2022Is Your Program Punitive? Fill Out a Grievance Report — It’s Time To Educate Them! Does Your Program Treat Patients With Dignity? Fill Out a Compliment Report — Let Them Know They are Appreciated! The Grievance Report Project is an ongoing project used to educate the Medication Assisted Treatment (MAT) community about quality treatment….
Patient Success Stories in Outpatient Medication-Assisted Treatment (MAT)
ByAdminAdmin 03/10/2026Substance use disorders, particularly opioid dependence, remain a major public health challenge worldwide. One of the most effective and evidence-based approaches to treating opioid addiction is Medication-Assisted Treatment (MAT). MAT combines FDA-approved medications with counseling and behavioral therapies to treat substance use disorders comprehensively. Outpatient MAT programs allow patients to receive treatment while continuing their…