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Keppra/Levetiracetam and methadone?
http://www.methadone.org/wespeakmethadone/viewtopic.php?f=2&t=896
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Author:  sapphire [ Fri Jan 22, 2016 7:37 am ]
Post subject:  Keppra/Levetiracetam and methadone?

Does anyone have any knowledge or experience with Levetiracetam/Keppra and methadone when prescribed together?

I am prescribed both, and in the UK BNF, which is like the prescriber's bible as far as side effects/interactions/costs etc of medications, it mentions nothing about Keppa being an enzyme inhibitor/inducer, as other meds like Topimarate and Valproic Acid are.

That said, my methadone prescriber thinks that as Keppra is one of the newer epilepsy drugs, and that it's really only started being widely prescribed in the UK quite recently, that it could well be, but we just don't know about it yet.

So, if anyone has been prescribed it, I'd be grateful to hear your experiences, as I think that when I have to increase my dose of Keppra, that it affects my methadone dose and I need to increase that also.

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